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The NHS in England has begun offering the first drug designed to assist people with multiple sclerosis (MS) in improving their ability to walk. Fampridine works by enhancing nerve signals, which helps some individuals move more easily and maintain greater independence in their daily lives.
Multiple sclerosis occurs when the immune system attacks the myelin sheath, a protective layer surrounding nerve cells. This damage disrupts the transmission of electrical messages from the brain to the body, including those needed to precisely control muscles involved in walking. Known as a “signal booster,” fampridine helps support these remaining electrical signals to pass through more effectively. Clinical trials found that about 40% of patients experienced better walking speed and endurance while using the drug, which can mean the difference between requiring assistance at home or being able to go out and socialize with friends and family.
Previously, the NHS in England decided not to fund fampridine, citing concerns about its cost-effectiveness. However, the medicine has been accessible in other parts of the UK, such as Wales, Scotland, and Northern Ireland. Now, up to 5,000 people each year in England are expected to benefit from this treatment. Before continuing the therapy, patients will undergo a trial period of up to one month to determine if they demonstrate a “clear benefit” from the medication.
Aysen Slack, 65, from Eastbourne, previously paid for fampridine privately but had to stop due to the high costs. She expressed optimism about the new NHS provision, saying, “My mobility has decreased a lot and even in my flat I have to use sticks now. It would make a huge difference to my life if I were able to improve my walking.” Prof Frankie Swords, the NHS national medical director, noted the significance of this development, stating that walking difficulties deeply affect the independence of those with MS, and that even modest improvements could greatly enhance daily life. Ceri Smith from the MS Society also welcomed the news, highlighting the drug’s potential to help people live more independently or remain in employment
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