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The study identified a problem with the womb lining, or endometrium, that can be passed down through generations. It has been found to make the womb ‘unwelcoming’ for an embryo to implant, leading to miscarriage.
“This is a very important step forward in understanding the cause of pregnancy loss and should give hope to women,” said the University of Warwick’s Professor Jan Brosens, who led the study.
The breakthrough could allow women to be tested for the genetic mutation responsible for the womb lining’s dysfunction, leading to tailored treatments and new hope for those affected by recurrent miscarriage.
“This allows for personalized treatments that correct the problem and prevent further miscarriage,” said co-researcher Dr Sarah Lloyd.
“This scientific discovery is truly something to celebrate,” said the charity Tommy’s, which funds work supporting families experiencing pregnancy complications.
Image: Charlie Beattie