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A new study focusing on potential severe side effects of weight loss injections has been initiated following numerous reports of pancreas-related issues. The Medicines and Healthcare Regulatory Agency (MHRA) and Genomics England are urging individuals who have experienced acute pancreatitis requiring hospitalization while on weight loss medications to come forward.
While there have been numerous reports of both acute and chronic pancreatitis linked to drugs like Mounjaro, Ozempic, and Wegovy, none have been definitively attributed to the medicines. Dr. Alison Cave, the MHRA’s chief safety officer, stated that the objective is to “better predict those most susceptible to adverse reactions.”
The investigation is being conducted through the MHRA’s Yellow Card program, which permits anyone to report problems with a medication, vaccine, or medical device to identify potential safety issues early on. Patients over the age of 18 who have experienced negative reactions to weight loss injections, which are also approved for individuals with type 2 diabetes, are encouraged to provide details on the Yellow Card website.
Those willing to participate in the study will be asked to provide additional information and a saliva sample to determine if certain individuals are at increased genetic risk of acute pancreatitis when using these medications. The ultimate goal is to minimize the occurrence of such side effects in the future, as per the MHRA
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